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Dendrite Blastoma Farming in Warframe (2026): Barbisteo in the Drift Caves
Spear Barbisteo in the caves, then fillet at Daughter
Last Updated on September 30, 2026
The short answer
Dendrite Blastoma comes from two Cambion Drift cave fish: Barbisteo and Vitreospina. Barbisteo is common and needs no bait, so spear it in any cave pool at either cycle and cut the fish at Daughter. Gauss gets you between pools quickly.
Reviewed September 29, 2026, current through Update 44 (Iceblade of Narin); node and mission types checked against the live star chart. This page is re-checked after every major patch.
| Where | Mission | Why |
|---|---|---|
| Cave pools, Barbisteo (Cambion Drift) | Spear it in a cave, Fass or Vome, no bait | Common fish, and it gives Dendrite Blastoma at every size. |
| Cave pools, Vitreospina (Cambion Drift) | Spear it in a cave with Fass Residue as bait | Uncommon fish that also yields Spinal Core Section. |
| Spitia Infested Cysts (Cambion Drift) | Break the cyst | A rare extra source while you are out there. |
Table of Contents
Every place it drops
Dendrite Blastoma drops on: Cambion Drift.
The fast route
- Equip a Spari or Ebisu spear.
- Go into a Cambion Drift cave. Barbisteo shuns the light, so stay inside.
- Spear Barbisteo in the cave pools. It works at either cycle and needs no bait.
- For Vitreospina, throw Fass Residue into the pool first.
- Take your fish to Daughter in the Necralisk and cut them for parts.
Best farming frames
| Frame | Role | Why |
|---|---|---|
| Gauss | Fast mover | Mach Rush is a hyper-sprint that gets you between veins, pools and vaults quickly. |
| Volt | Fast mover | Speed gives a short movement boost to you and your squad. |
Tips that save runs
- Both fish live in caves. Fishing the open surface will not find them.
- Barbisteo gives one Dendrite Blastoma at every size, so take the fish you can catch fastest.
Mistakes that waste runs
- Fishing the surface pools. Barbisteo and Vitreospina are cave fish.
- Skipping Fass Residue when chasing Vitreospina.
What it builds
| Item | Note |
|---|---|
| Desus Antigen | Needs 15 Dendrite Blastoma. |
| Iranon Antigen | Needs 15 Dendrite Blastoma. |
| Sepulcrum Receiver | Needs 20 Dendrite Blastoma. |
| Palmaris and Vermisplicer | Kitgun parts, 10 each. |
| Zymos Barrel | Needs 8 Dendrite Blastoma. |