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Best Warframe for Infested Salvage (2026)

Top frames, weapons, stat priorities and mods for Infested Salvage

Last Updated on September 20, 2026

The short answer

Nekros is the first pick: Desecrate turns corpses into extra drops, which keeps the Antiserum flowing, and the health orbs keep you alive while you run between vaporizers. Octavia and Nova make the room safe. This is the mode that drops Nidus, and since Update 42 his parts come from rotations A and B as well as C.

Researched September 19, 2026, current through Update 43.5. Picks need two independent sources; anything we could only confirm once is left out.

FrameWhyBuild focus
NekrosDesecrate raises the supply of Antiserum Charges so the vaporizer bubbles stay up, and drops health orbs on the side.range high
OctaviaMallet and Resonator pull the Infested away from the consoles, and Metronome's invisibility lets you carry charges unbothered.duration high
NovaMolecular Prime slows the rush at the console room and buys time to refill a vaporizer before a console takes damage.strength high, duration high, range high
HydroidTentacle Swarm locks down part of the room so you can deposit charges without interruption.range high
KhoraStrangledome holds a wide area beside a console or vaporizer.range high

The picks

1. Nekros

Desecrate raises the supply of Antiserum Charges so the vaporizer bubbles stay up, and drops health orbs on the side.

Strength: lowDuration: midEfficiency: midRange: high

9
Despoil
Despoil
Desecrate Augment: No longer consumes Energy, but consumes 10 Health per corpse instead.
Nekros
9
Stretch
Stretch
+45% Ability Range
WARFRAME
14
Primed Continuity
Primed Continuity
+55% Ability Duration
WARFRAME
13
Constitution
Constitution
+40% Faster Knockdown Recovery
+28% Ability Duration
WARFRAME

2. Octavia

Mallet and Resonator pull the Infested away from the consoles, and Metronome's invisibility lets you carry charges unbothered.

Strength: midDuration: highEfficiency: midRange: mid

14
Primed Continuity
Primed Continuity
+55% Ability Duration
WARFRAME
13
Constitution
Constitution
+40% Faster Knockdown Recovery
+28% Ability Duration
WARFRAME
9
Stretch
Stretch
+45% Ability Range
WARFRAME
16
Narrow Minded
Narrow Minded
+99% Ability Duration
-66% Ability Range
WARFRAME

3. Nova

Molecular Prime slows the rush at the console room and buys time to refill a vaporizer before a console takes damage.

Strength: highDuration: highEfficiency: midRange: high

9
Stretch
Stretch
+45% Ability Range
WARFRAME
11
Overextended
Overextended
+90% Ability Range
-60% Ability Strength
WARFRAME
9
Streamline
Streamline
+30% Ability Efficiency
WARFRAME
11
Fleeting Expertise
Fleeting Expertise
+60% Ability Efficiency
-60% Ability Duration
WARFRAME

4. Hydroid

Tentacle Swarm locks down part of the room so you can deposit charges without interruption.

Strength: midDuration: midEfficiency: midRange: high

9
Pilfering Swarm
Pilfering Swarm
Tentacle Swarm Augment: Enemies held by tentacles have a 100% chance at additional drops.
Hydroid
9
Stretch
Stretch
+45% Ability Range
WARFRAME
14
Primed Continuity
Primed Continuity
+55% Ability Duration
WARFRAME

5. Khora

Strangledome holds a wide area beside a console or vaporizer.

Strength: midDuration: midEfficiency: midRange: high

9
Pilfering Strangledome
Pilfering Strangledome
Strangledome Augment: Enemies held in Strangledome have a 65% chance of dropping additional loot.
Khora
9
Stretch
Stretch
+45% Ability Range
WARFRAME
14
Primed Continuity
Primed Continuity
+55% Ability Duration
WARFRAME

Best weapons

WeaponWhy
ToridGas clouds stack status down the corridors the Infested run through.
Kuva ZarrHeavy area clear for tight rooms.
Kuva BrammaThe same job, from range.
StrunWith its Incarnon form, reliable close-range crowd clear.
Proboscis CernosArrows pull enemies together so your area damage lands on all of them.

Tips that save runs

  • Three consoles, three vaporizers. Put one player on each and let a fourth run charges.
  • You carry three Antiserum Charges at most. Deposit often.
  • Stay inside a bubble. Outside it the room corrodes your armor, and it corrodes unprotected consoles to death.
  • Top a bubble up before it collapses; they shrink over time.
  • Nidus parts now drop on rotations A and B too, but C still has the best odds.

Mistakes that waste runs

  • Letting a bubble collapse and a console sit exposed. That is how the mission is lost.
  • The whole squad crowding one console while two corrode.
  • Leaving after rotation A when you are farming Nidus.

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