How to Get Mesa in Warframe (2026): Blueprint, Parts and Mesa Prime
Last Updated on September 11, 2026
Mesa: Market for Platinum, or Circuit tier 10. Run Patient Zero once, stockpile Nav Coordinates, then chain the key fights. Mesa Prime: Mesa Prime is vaulted; Prime Resurgence or trading only.
Reviewed September 10, 2026, current through Update 43.5. Iceblade of Narin lands September 23 and is not reflected yet; acquisition is re-checked after every major patch.
| What | Where |
|---|---|
| Main blueprint | Market for Platinum, or Circuit tier 10 |
| Parts | Neuroptics: Mutalist Alad V Assassination on Eris (about 39%); Chassis: Mutalist Alad V Assassination on Eris (about 39%); Systems: Mutalist Alad V Assassination on Eris (about 23%) |
| Requirements | Patient Zero quest, which gives the Assassinate Key blueprint; One Mutalist Alad V Nav Coordinate per key, from Infested Invasions or Deimos missions |
| Prime | Mesa Prime is vaulted; Prime Resurgence or trading only. |
How to get Mesa, step by step
- Requirement: Patient Zero quest, which gives the Assassinate Key blueprint
- Requirement: One Mutalist Alad V Nav Coordinate per key, from Infested Invasions or Deimos missions
- Main blueprint: Market for Platinum, or Circuit tier 10
- Neuroptics: Mutalist Alad V Assassination on Eris (about 39%)
- Chassis: Mutalist Alad V Assassination on Eris (about 39%)
- Systems: Mutalist Alad V Assassination on Eris (about 23%)
- Build the parts in the Foundry (12 hours each), then the frame (72 hours), or rush with platinum. The finished frame is also on the Market for platinum.
Parts and where they drop
| Part | Source |
|---|---|
| Neuroptics | Mutalist Alad V Assassination on Eris (about 39%) |
| Chassis | Mutalist Alad V Assassination on Eris (about 39%) |
| Systems | Mutalist Alad V Assassination on Eris (about 23%) |
Every attempt burns a key built from a Nav Coordinate, so the boss cannot be spammed; farm coordinates first.
What you get: Mesa's abilities
Ballistic BatteryAbility 1
Shooting GalleryAbility 2
Shatter ShieldAbility 3
PeacemakerAbility 4Mesa Prime: which relics hold each part
Every relic that has ever held the part. Vaulted relics only come from Varzia's Prime Resurgence or trading; the live pages below show what is open right now.
| Part | Relics |
|---|---|
| Mesa Prime Blueprint | Vanguard P1, Neo Z3, Neo Z2, Meso R2, Meso P3, Lith C6, Lith P7, Lith N9, Lith D1 |
| Mesa Prime Neuroptics | Axi M4, Axi M3, Vanguard M1, Lith M5, Lith M3, Lith M4 |
| Mesa Prime Chassis | Axi M1, Axi H4, Vanguard E1, Neo R4, Neo C1, Neo A3, Meso L2, Meso C4, Lith R1, Lith S10 |
| Mesa Prime Systems | Vanguard C1, Neo H3, Lith D5, Neo M3, Neo M2, Lith M6 |
Is Mesa worth it in 2026?
S tier on our list: Peacemaker deletes crowds while Shatter Shield keeps her standing forever.
Related
- Mesa: abilities, stats and builds
- Warframe tier list 2026
- Best Warframe for Disruption
- Best Warframe for Exterminate
- Best Warframe for Assassination
- Prime Resurgence: Varzia's rotation
- Void fissures right now
- Best starter Warframe and what to get next
- Progression map: what unlocks what
Table of Contents