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Home Warframe Nidus

NIDUS

Nidus draws strength from the Infestation. It bolsters him with survivability as he deals high damage and provides crowd control. Plague your enemies.

Nidus stacks Mutation by spamming Virulence, then locks Parasitic Link onto himself or an ally with the Parasitic Vitality augment to turn into a near-unkillable tank, while Larva clumps enemies for easy kills. He's a self-sufficient Steel Path survival and crowd-control frame, not a burst damage dealer, and barely needs energy once his stacks are built up.

NIDUS
Energy200
Health775
Shield100
Sprint Speed1
Duration100%
Efficiency100%
Range100%
Strength100%
Armor350
Damage Reduction53.8%
Effective Hit Points1,813
PassiveInnateIf Nidus is killed with at least 15 stacks of Mutation, those 15 stacks are consumed; this grants 5s of invulnerability and restores Health to 50%.
Virulence
Ability 1VirulenceRupture the ground with a damaging fungal growth that steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates, multiplying its destructive force.Energy40Initial Damage200Lingering Damage100/sRange16mDuration5s
Larva
Ability 2LarvaHelminthSpawn an Infested pod that erupts with tendrils, latches onto nearby enemies and pulls them in. Enemies killed while held have a chance of generating a Mutation stack.Energy25Range12mDuration7sMutation Chance50%
Parasitic Link
Ability 3Parasitic LinkBind to a target with parasitic link. When cast on an ally, both the host and Nidus have their Ability Strength and Weapon Damage increased. Linked enemies take some of the damage inflicted on Nidus.Energy25Duration60sRange40mDamage Bonus25%Damage Redirect50%
Ravenous
Ability 4RavenousGluttonous maggots swarm nearby enemies, feasting until they are hit with Virulence and burst with Infestation. The maggots benefit from Mutation and each enemy hit adds to the Mutation stack.Energy0 (3 Mutation stacks)Explosion Damage150Duration40sRange8mMaggot Health1000
HelminthFeed a spare Nidus to the Helminth and every other Warframe can run Larva. Prime and Umbra frames cannot be subsumed.Best subsumes
Most popular mods
16
Blind Rage
Blind Rage
+99% Ability Strength
-55% Ability Efficiency
WARFRAME
16
Umbral Intensify
Umbral Intensify
+44% Ability Strength
+11% Tau Resistance
Enhance mods in this set.
SET: WARFRAME
16
Umbral Vitality
Umbral Vitality
+100% Health
+11% Tau Resistance
Enhance mods in this set.
SET: WARFRAME
16
Umbral Fiber
Umbral Fiber
+100% Armor
+11% Tau Resistance
Enhance mods in this set.
SET: WARFRAME
12
Adaptation
Adaptation
When Damaged: +10% Resistance to that Damage Type for 20s. Stacks up to 90%.
WARFRAME
11
Hunter Adrenaline
Hunter Adrenaline
Convert +45% of Damage on Health to Energy. Without Shields, ally Overguard imitates Health.
+150% Companion Damage on enemies affected by Slash.
SET: WARFRAME
9
Stretch
Stretch
+45% Ability Range
WARFRAME
9
Parasitic Vitality
Parasitic Vitality
Parasitic Link Augment: Nidus and any ally he's bound to gain 4% Max Health per Mutation during Parasitic Link.
Nidus

Based on several sources, these are the mods most commonly run on Nidus. They do not reflect a complete build.

NIDUS builds
Top community builds for NIDUSRanked, voted builds on Overframe.gg→Open

Community builds live on Overframe.gg. Link opens on their site.

NIDUS PRIME

Mutation is endless. The ravening plague-bearer returns in a long-unseen form, seething with a primal strain of the Infestation.

Nidus stacks Mutation by spamming Virulence, then locks Parasitic Link onto himself or an ally with the Parasitic Vitality augment to turn into a near-unkillable tank, while Larva clumps enemies for easy kills. He's a self-sufficient Steel Path survival and crowd-control frame, not a burst damage dealer, and barely needs energy once his stacks are built up.

NIDUS PRIME
Energy240
Health925
Shield100
Sprint Speed1
Duration100%
Efficiency100%
Range100%
Strength100%
Armor425
Damage Reduction58.6%
Effective Hit Points2,369
VaultedRelics no longer drop; trade for the set or wait for Prime Resurgence.Released Sep 8, 2021, Update 30.7Set: 90p on warframe.marketRelicsAll prices
PassiveInnateIf Nidus is killed with at least 15 stacks of Mutation, those 15 stacks are consumed; this grants 5s of invulnerability and restores Health to 50%.
Virulence
Ability 1VirulenceRupture the ground with a damaging fungal growth that steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates, multiplying its destructive force.Energy40Initial Damage200Lingering Damage100/sRange16mDuration5s
Larva
Ability 2LarvaHelminthSpawn an Infested pod that erupts with tendrils, latches onto nearby enemies and pulls them in. Enemies killed while held have a chance of generating a Mutation stack.Energy25Range12mDuration7sMutation Chance50%
Parasitic Link
Ability 3Parasitic LinkBind to a target with parasitic link. When cast on an ally, both the host and Nidus have their Ability Strength and Weapon Damage increased. Linked enemies take some of the damage inflicted on Nidus.Energy25Duration60sRange40mDamage Bonus25%Damage Redirect50%
Ravenous
Ability 4RavenousGluttonous maggots swarm nearby enemies, feasting until they are hit with Virulence and burst with Infestation. The maggots benefit from Mutation and each enemy hit adds to the Mutation stack.Energy0 (3 Mutation stacks)Explosion Damage150Duration40sRange8mMaggot Health1000
Most popular mods
16
Blind Rage
Blind Rage
+99% Ability Strength
-55% Ability Efficiency
WARFRAME
16
Umbral Intensify
Umbral Intensify
+44% Ability Strength
+11% Tau Resistance
Enhance mods in this set.
SET: WARFRAME
16
Umbral Vitality
Umbral Vitality
+100% Health
+11% Tau Resistance
Enhance mods in this set.
SET: WARFRAME
16
Umbral Fiber
Umbral Fiber
+100% Armor
+11% Tau Resistance
Enhance mods in this set.
SET: WARFRAME
12
Adaptation
Adaptation
When Damaged: +10% Resistance to that Damage Type for 20s. Stacks up to 90%.
WARFRAME
11
Hunter Adrenaline
Hunter Adrenaline
Convert +45% of Damage on Health to Energy. Without Shields, ally Overguard imitates Health.
+150% Companion Damage on enemies affected by Slash.
SET: WARFRAME
9
Stretch
Stretch
+45% Ability Range
WARFRAME
9
Parasitic Vitality
Parasitic Vitality
Parasitic Link Augment: Nidus and any ally he's bound to gain 4% Max Health per Mutation during Parasitic Link.
Nidus

Based on several sources, these are the mods most commonly run on Nidus. They do not reflect a complete build.

NIDUS PRIME builds
Top community builds for NIDUS PRIMERanked, voted builds on Overframe.gg→Open

Community builds live on Overframe.gg. Link opens on their site.

NIDUS PRIME blueprint
ItemCountSource
Nidus Prime Blueprint1
Axi A14 Relic11.00%
Meso P8 Relic11.00%
Meso N12 Relic11.00%
Meso R5 Relic11.00%
Lith R2 Relic11.00%
3 more…
Nidus Prime Neuroptics1
Neo S19 Relic11.00%
Axi N9 Relic (Radiant)10.00%
Axi N10 Relic (Radiant)10.00%
Neo N16 Relic (Radiant)10.00%
Nidus Prime Chassis1
Axi N12 Relic (Radiant)10.00%
Neo N18 Relic (Radiant)10.00%
Meso N13 Relic (Radiant)10.00%
Meso N14 Relic (Radiant)10.00%
Lith N7 Relic (Radiant)10.00%
1 more…
Nidus Prime Systems1
Neo N19 Relic25.33%
Neo C2 Relic25.33%
Neo A8 Relic25.33%
Meso P9 Relic25.33%
Meso B5 Relic25.33%
3 more…
Orokin Cell1
Common resource drop

Relic drop chances shown at the tier players usually farm each part. Data from the game files, refreshed each patch.